Palace Akropolis

Whenever good independent bands tour through Prague, there's a very good chance they'll be playing at Palace Akropolis. The venue is medium-sized, with a large and small stage - so you can catch a touring band from the U.K. one night and then a local singer/songwriter the next night, all in one place. The so-called "cultural complex" consists of an independent theatre, a concert hall, a cinema and an exhibition space for art openings and the like. Though re-opened in 1996, its historic roots go back to the pre-war Akropolis theatre, closed to the public and abandoned in 1948 and deteriorated until its re-construction in the early 90s. For more popular touring bands, be sure to get your tickets early, as the venue does sell out quite often.

where can i find partypictures of the night in akropolis? there where a man who made some pictures...

...again a little off the center but worth the detour - maybe the best place for funk, hip hop & latino in Prague (check out their website for the schedule : http://www.palacakropolis.com/program).
Best time to hit Acropolis is around midnight - it's always busy and rather crowded on weekends. This is where the best local DJs and soundsystems play.

a true indie atmosphere in prague. be sure to start out early as it's a bit of a hike from the centre, but it's the best place to catch awesome live bands - mew played there!!